162. Cyclic Allene Approach to the Manzamine Alkaloid Keramaphidin B

Milauni M. Mehta, Jordan A. M. Gonzalez, James L. Bachman, and Neil K. Garg. Org. Lett. 2023, 25, 5553–5557.


161. Total Synthesis of Phenanthroindolizidines Using Strained Azacyclic Alkynes

Katie A. Spence, Marie Hoffmann, and Neil K. Garg. Org. Lett. 2023, 25, 5044–5048.


157. Total Synthesis of Lissodendoric Acid A via Stereospecific Trapping of a Strained Cyclic Allene

Francesca M. Ippoliti,† Nathan J. Adamson,† Laura G. Wonilowicz, Daniel J. Nasrallah, Evan R. Darzi, Joyann S. Donaldson, and Neil K. Garg. Science 2023, 379, 261–265.

154. A Symmetry-Driven Approach Toward the Total Synthesis of Dodecahedrane

Jason V. Chari,† Luca McDermott,† Jacob E. Dander, Bryan J. Simmons, and Neil K. Garg. Tetrahedron 2022, 126, 133041–133046. (Special issue in honor of Professor John Wood)

142. Cell-Free Total Biosynthesis of Plant Terpene Natural Products using an Orthogonal Cofactor Regeneration System

Undramaa Bat-Erdene, John M. Billingsley, William C. Turner, Benjamin R. Lichman, Francesca M. Ippoliti, Neil K. Garg, Sarah E. O’Connor, and Yi Tang. ACS Catal. 2021, 11, 9898–9903.

137. Total Synthesis of (−)-Strictosidine and Interception of Aryne Natural Product Derivatives “Strictosidyne” and “Strictosamidyne”

Sarah M. Anthony,† Veronica Tona,† Yike Zou,† Lucas A. Morrill, John M. Billingsley, Megan Lim, Yi Tang,* K. N. Houk,* Neil K. Garg* J. Am. Chem. Soc. 2021, 143, 10, 7471–7479.

134. Taming Radical Pairs in the Crystalline Solid State: Discovery and Total Synthesis of Psychotriadine

Jordan J. Dotson, Ieva Liepuoniute, J. Logan Bachman, Vince M. Hipwell, Saeed I. Khan, K. N. Houk*, Neil K. Garg*, and Miguel A. Garcia-Garibay.* J. Am. Chem. Soc. 2021, 143, 10, 4043–4054.

124. Discovery and Total Synthesis of a Bis(Cyclotryptamine) Alkaloid Bearing the Elusive Piperidinoindoline Scaffold

Jordan J. Dotson, J. Logan Bachman, Miguel A. Garcia-Garibay, Neil K. Garg. J. Am. Chem. Soc. 2020, 142, 11685–11690.

122. Evaluation of the photodecarbonylation of crystalline ketones for the installation of reverse prenyl groups on the pyrrolidinoindoline scaffold

Jordan J. Dotson, Neil K. Garg, and Miguel A. Garcia Garibay. Tetrahedron 2020, 76, 131181.

107. Thioesterase-Catalyzed Aminoacylation and Thiolation of Polyketides in Fungi

Man-Cheng Tang, Curt R. Fischer, Jason V. Chari, Dan Tan, Sundari Suresh, Angela Chu, Molly Miranda, Justin Smith, Zhuan Zhang, Neil K. Garg, Robert P. St. Onge, and Yi Tang. J. Am. Chem. Soc. 2019, 141, 8198–8206.

102. Synthesis of 8-Hydroxygeraniol

Francesca M. Ippoliti, Joyann S. Barber, and Neil K. Garg. Org. Synth. 201996, 586–598.

100. Canvass: A Crowd-Sourced, Natural Product Screening Library for Exploring Biological Space

Sara E. Kearney, Gergely Zahoránszky-Kőhalmi, Kyle R. Brimacombe, Mark J. Henderson, Caitlin Lynch, Tongan Zhao, Kanny K. Wan, Zina Itkin, Christopher Dillon, Min Shen, Dorian M. Cheff, Tobie D. Lee, Danielle Bougie, Ken Cheng, Nathan P. Coussens, Dorjbal Dorjsuren, Richard T. Eastman, Ruili Huang, Michael J. Iannotti, Surendra Karavadhi, Carleen Klumpp-Thomas, Jacob S. Roth, Srilatha Sakamuru, Wei Sun, Steven A. Titus, Adam Yasgar, Ya-Qin Zhang, Jinghua Zhao, Rodrigo B. Andrade, M. Kevin Brown, Noah Z. Burns, Jin K. Cha, Emily E. Mevers, Jon Clardy, Jason A. Clement, Peter A. Crooks, Gregory D. Cuny, Jake Ganor, Jesus Moreno, Lucas A. Morrill, Elias Picazo, Robert B. Susick, Neil K. Garg, Brian C. Goess, Robert B. Grossman, Chambers C. Hughes, Jeffrey N. Johnston, Madeleine M. Joullié, A. Douglas Kinghorn, David G.I. Kingston, Michael J. Krische, Ohyun Kwon, Thomas J. Maimone, Susruta Majumdar, Katherine N. Maloney, Enas Mohamed, Brian T. Murphy, Pavel Nagorny, David E. Olson, Larry E. Overman, Lauren E. Brown, John K. Snyder, John A. Porco, Jr., Fatima Rivas, Samir A. Ross, Richmond Sarpong, Indrajeet Sharma, Jared T. Shaw, Zhengren Xu, Ben Shen, Wei Shi, Corey Stephenson, Alyssa L. Verano, Derek S. Tan, Yi Tang, Richard E. Taylor, Regan J. Thomson, David A. Vosburg, Jimmy Wu, William M. Wuest, Armen Zakarian, Yufeng Zhang, Tianjing Ren, Zhong Zuo, James Inglese, Sam Michael, Anton Simeonov, Wei Zheng, Paul Shinn, Ajit Jadhav, Matthew B. Boxer, Matthew D. Hall, Menghang Xia, Rajarshi Guha, and Jason M. Rohde. ACS Central Science 2018, 4, 1727–1741.

88. Engineering the Biocatalytic Selectivity of Iridoid Production in Saccharomyces cerevisiae

John M. Billingsley, Anthony B. DeNicola, Joyann S. Barber, Man-Cheng Tang, Joe Horecka, Angela Chu, Neil K. Garg, and Yi Tang. Metab. Eng. 201744, 117–125.

85. Indole Diterpenoid Natural Products as the Inspiration for New Synthetic Methods and Strategies

Michael A. Corsello,† Junyong Kim,† and Neil K. Garg. Chem. Sci20178, 5836–5844.

84. Total Synthesis of (–)-Tubingensin B Enabled by the Strategic Use of an Aryne Cyclization

Michael A. Corsello,† Junyong Kim,† and Neil K. Garg. Nat. Chem20179, 944–949.

79. Collaborative Biosynthesis of Maleimide- and Succinimide-Containing Natural Products by Fungal Polyketide Megasynthases

Michio Sato, Jacob E. Dander, Chizuru Sato, Yiu-sun Hung, Shu-Shan Gao, Man-Cheng Tang, Leibniz Hang, Jaclyn M. Winter, Neil K. Garg, Kenji Watanabe, and Yi Tang. J. Am. Chem. Soc. 2017139, 5317–5320.

77. Enzyme-Catalyzed Stereoselective Intramolecular Hydroalkoxylation

Shu-Shan Gao, Marc Garcia-Borràs, Joyann S. Barber, Yang Hai, Abing Duan, Neil K. Garg, K. N. Houk, and Yi Tang. J. Am. Chem. Soc. 2017139, 3639–3642.

73. Pardon the Interruption: A Modification of Fischer’s Venerable ­Reaction for the Synthesis of Heterocycles and Natural Products

Robert B. Susick,† Lucas A. Morrill,† Elias Picazo,† and Neil K. Garg. Synlett 201728, 1–11.

64. P450-Mediated Coupling of Indole Fragments to Forge Communesin and Unnatural Isomers

 Hsiao-Ching Lin, Travis C. McMahon, Ashay Patel, Michael Corsello, Adam Simon, Wei Xu, Muxun Zhao, K. N. Houk, Neil K. Garg, and Yi Tang. J. Am. Chem. Soc2016138, 4002–4005

56. Fischer Indolizations as a Strategic Platform for the Total Synthesis of Picrinine

Joel M. Smith, Jesus Moreno, Ben W Boal, and Neil K. Garg. J. Org. Chem. 2015, 80, 8954–8967. (Featured Article)

54. Elucidation of the Concise Biosynthetic Pathway of the Communesin Indole Alkaloids

Hsiao-Ching Lin, Grace Chiou, Yit-Heng Chooi, Travis C. McMahon, Wei Xu, Neil K. Garg, and Yi Tang. 
Angew. Chem. Int. Ed. 201554, 3004–3007. (Selected as a Very Important Paper)

44. Total Synthesis of the Akuammiline Alkaloid Picrinine

Joel M. Smith, Jesus Moreno, Ben W. Boal, and Neil K. Garg. J. Am. Chem. Soc. 2014136, 4504–4507

43. Concise Enantiospecific Total Synthesis of Tubingensin A

Adam E. Goetz,† Amanda L. Silberstein,† Michael A. Corsello, and Neil K. Garg. J. Am. Chem. Soc. 2014136, 3036–3039

42. Total Syntheses of Indolactam Alkaloids (–)-Indolactam V, (–)-Pendolmycin, (–)-Lyngbyatoxin A, and (–)-Teleocidin A-2

Noah F. Fine Nathel,† Tejas K. Shah,† Sarah M. Bronner, and Neil. K. Garg. Chem. Sci. 20145, 2184–2190

39. Enantiospecific Total Synthesis of N-Methylwelwitindolinone D Isonitrile

Evan D. Styduhar, Alexander D. Huters, Nicholas A. Weires, and Neil K. Garg. Angew. Chem. Int. Ed. 201352, 12422–12425

37. Expanding the Structural Diversity of Polyketides by Exploring the Cofactor Tolerance of an Inline Methyltransferase Domain

Jaclyn M. Winter, Grace Chiou, Ian R. Bothwell,, Wei Xu, Neil K. Garg, Minkui Luo, and Yi Tang. Org. Lett. 201315, 3774–3777

36. EcdGHK are Three Tailoring Iron Oxygenases for Amino Acid Building Blocks of the Echinocandin Scaffold

Wei Jiang, Ralph A. Cacho, Grace Chiou, Neil K. Garg, Yi Tang, and Christopher T. Walsh. J. Am. Chem. Soc. 2013135, 4457–4466

32. Identification and Characterization of the Chaetoviridin and Chaetomugilin Gene Cluster in Chaetomium globosum Reveal Dual Functions of an Iterative Highly-Reducing Polyketide Synthase

Jaclyn M. Winter, Michio Sato, Satoru Sugimoto, Grace Chiou, Neil K. Garg, Yi Tang, and Kenji Watanabe. 
J. Am. Chem. Soc. 2012134, 17900–17903

26. Total Syntheses of the Elusive Welwitindolinones with Bicyclo[4.3.1]cores

Alexander D. Huters, Evan D. Styduhar, and Neil K. Garg. Angew. Chem. Int. Ed. 201251, 3758–3765

24. Total Synthesis of Oxidized Welwitindolinones and (–)-N-Methylwelwitindolinone C Isonitrile

Kyle W. Quasdorf, Alexander D. Huters, Michael W. Lodewyk, Dean J. Tantillo, and Neil K. Garg. J. Am. Chem. Soc. 2012134, 1396–1399

23. Synthesis of (+)-Phenserine using an Interrupted Fischer Indolization Reaction

Alex W. Schammel, Grace Chiou, Neil K. Garg. J. Org. Chem. 201277, 725–728

22. Total Synthesis of (–)-N-Methylwelwitindolinone C Isothiocyanate

Alexander D. Huters, Kyle W. Quasdorf, Evan D. Styduhar, and Neil K. Garg. J. Am. Chem. Soc2011133, 15797–15799

19. Total Synthesis of (±)-Aspidophylline A

Liansuo Zu, Ben W. Boal, and Neil K. Garg. J. Am. Chem. Soc. 2011133, 8877–8879

15. A Fungal Nonribosomal Peptide Synthetase Module that can Synthesize Thiopyrazines

Kangjian Qiao, Hui Zhou, Wei Xu, Wenjun Zhang, Neil K. Garg, and Yi Tang. Org. Lett. 201113, 1758–1761